Firefighters responded to a building fire on Rosslyn Street in West Melbourne shortly after 3pm this afternoon.
Fire Rescue Victoria (FRV) crews arrived in six minutes to find smoke and flames issuing from a storage building underneath the Dudley Street railway bridge.
Firefighters wearing breathing apparatus entered the building and found various equipment and contents on fire.
A search confirmed no persons inside.
Trains were halted while firefighters fought the fire and later inspected the rail line for fire extension.
Trains have now resumed. There are residual delays for both metropolitan and V/Line services that traverse via North Melbourne Station.
The fire was contained to the contents of the building.
Firefighters were able to quell the flames and bring the fire under control at 3.33pm, 28 minutes after arriving on the scene.
No injuries have been reported.
The cause of the fire is yet to be determined. It will be investigated.
