Mernda police are appealing for public assistance to help locate missing 39-year-old Doreen woman Leesa Grozdan.
Leesa was last seen driving a white Ford Ranger in Doreen around 8am Wednesday (3 April).
She is described as being Caucasian in appearance with brown hair and blue eyes.
Police and family have concerns for her welfare due to medical conditions.
Anyone who sights Leesa or has information on her current whereabouts is urged to contact Mernda Police Station on (03) 9216 1200.