Police are investigating a fatal collision between a vehicle and motorcycle on Marysville-Woods Point Road, Marysville just before 3pm.
The yet to be identified male motorcyclist died at the scene, no one else was injured.
The exact cause of the incident is yet to be determined.
Anyone with information or witnessed the accident is urged to contact Crime Stoppers on 1800 333 000 or submit an online report at www.crimestoppersvic.com.au.